Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459987 | 1.00 | SLC6A4 (0.46) | SLC6A4TAAR1SLC6A2SLC6A3MAPK9 | |
| SCHEMBL11661953 | 0.80 | SLC6A4 (0.51) | SLC6A4TAAR1SLC6A2SLC6A3MAPK9 | |
| SCHEMBL12261523 | 0.78 | TAAR1 (0.51) | SLC6A4TAAR1SLC6A2SLC6A3MAPK9 | |
| SCHEMBL15262576 | 0.78 | CYP3A4 (0.51) | SLC6A4TAAR1SLC6A2SLC6A3MAPK9 | |
| SCHEMBL15262580 | 0.78 | CYP3A4 (0.51) | SLC6A4TAAR1SLC6A2SLC6A3MAPK9 | |
| SCHEMBL13144655 | 0.78 | TAAR1 (0.51) | SLC6A4TAAR1SLC6A2SLC6A3MAPK9 | |
| SCHEMBL12261666 | 0.78 | TAAR1 (0.51) | SLC6A4TAAR1SLC6A2SLC6A3MAPK9 | |
| SCHEMBL7420094 | 0.75 | TAS1R3 (0.50) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL5469966 | 0.75 | TAS1R3 (0.50) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 | |
| SCHEMBL20789018 | 0.75 | AOC3 (0.51) | SLC6A4TAAR1SLC6A2SLC6A3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242389-B1 | NOVEL BRANCHED SUBSTITUTED AMINO DERIVATIVES OF 3-AMINO-1-PHENYL-1H[1,2,4]TRIAZOL, METHODS FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI SYNTHELABO (FR) | 2004-04-21 | — | — | EP | disclosed |
| CN-1434808-A | Novel branched substituted amino derivatives of 3-amino-1-phemyl-1H[1,2,4]triazo, methods for producing them and pharmaceutica compositions containing them | SANOFI SYNTHELABO (FR) | 2003-08-06 | — | — | CN | disclosed |
| EP-1242389-A2 | NOVEL BRANCHED SUBSTITUTED AMINO DERIVATIVES OF 3-AMINO-1-PHENYL-1H[1,2,4]TRIAZOL, METHODS FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044207-A2 | NOVEL BRANCHED SUBSTITUTED AMINO DERIVATIVES OF 3-AMINO-1-PHENYL-1H[1,2,4]TRIAZOL, METHODS FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 2001-06-21 | — | — | WO | disclosed |