SCHEMBL6564078

SCHEMBL6564078

COC(=O)c1ccc2c(=O)oc(-c3ccc(-c4nc5cc(C(=O)OC)ccc5c(=O)o4)cc3)nc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.56
MAPT P10636 7/20 0.56
KDM4E B2RXH2 7/20 0.56
RAB9A P51151 5/20 0.56
NPC1 O15118 5/20 0.56
SMN1; SMN2 Q16637 4/20 0.56
HPGD P15428 4/20 0.56
HSD17B10 Q99714 2/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
ATM Q13315 1/20 0.56
TP53 P04637 2/20 0.55
LMNA P02545 1/20 0.51
GPR119 Q8TDV5 1/20 0.48
HSPD1 P10809 1/20 0.47
PTPN2 P17706 1/20 0.47
PTPN1 P18031 1/20 0.47
PTPN5 P54829 1/20 0.47
HSPE1 P61604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6106602 0.92 HDAC6 (0.55) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL6567148 0.83 ELANE (0.55) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL6108114 0.82 HDAC6 (0.55) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL7610004 0.81 MAPT (0.81) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL6594806 0.78 ELANE (0.65) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL11544615 0.77 MAPT (0.73) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL5539855 0.77 ALDH1A1 (0.47) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL5638115 0.76 MAPT (0.70) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL19029474 0.76 MAPT (0.86) ALDH1A1MAPTKDM4ERAB9ANPC1
SCHEMBL19029465 0.76 HDAC6 (0.73) ALDH1A1MAPTKDM4ERAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed