Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14453837 | 0.88 | BCL9 (0.65) | BCL9CTNNB1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL14962749 | 0.84 | BCL9 (0.60) | BCL9CTNNB1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL19201779 | 0.81 | BCL9 (0.65) | BCL9CTNNB1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL5466190 | 0.80 | BCL9 (0.56) | BCL9CTNNB1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL515913 | 0.80 | GAA (0.57) | BCL9CTNNB1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL9435291 | 0.80 | GAA (0.57) | BCL9CTNNB1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL4076398 | 0.79 | BCL9 (0.66) | BCL9CTNNB1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL27675916 | 0.79 | LMNA (0.50) | GAAKMT2ANPC1MAPTALDH1A1 | |
| SCHEMBL2294100 | 0.79 | BCL9 (0.76) | BCL9CTNNB1GAAKMT2ASMN1; SMN2 | |
| SCHEMBL27713294 | 0.79 | BCL9 (0.70) | BCL9CTNNB1GAAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147076-B1 | ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES | OKANO TERUO PROF (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6495645-B1 | INCORPORATING MANY SIDE FUNCTIONAL GROUPS WHILE MAINTAINING SENSITIVE TEMPERATURE RESPONSE | Okano, Terou (JP) | 2002-12-17 | — | — | US | disclosed |