Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11327941 | 0.83 | — | — | |
| SCHEMBL6564566 | 0.83 | — | — | |
| SCHEMBL6152756 | 0.83 | — | — | |
| SCHEMBL28666055 | 0.81 | — | — | |
| SCHEMBL8722348 | 0.81 | ALDH1A1 (0.37) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL9465029 | 0.78 | ZDHHC7 (0.48) | TDP1CYP3A4TSHRZDHHC7LCK | |
| Methoxymethane SCHEMBL7865469 | 0.78 | ZDHHC7 (0.36) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL7537810 | 0.78 | CHRM1 (0.33) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3413684 | 0.76 | ALDH1A1 (0.43) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL28002469 | 0.76 | MGAM (0.43) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0981958-B1 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEM RES (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-6548511-B1 | Anilinopyrimidinone derivatives of given formula such as 2-(2,5-bis(trifluoromethyl)phenyl)amino-5-chloro-3-isobutyl-6 -trifluoromethyl-4(3H)-pyrimidinone; controlling pests of agricultural and horticultural products | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-04-15 | — | — | US | disclosed |
| EP-0981958-A1 | INSECTICIDAL/ACARICIDAL AGENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2000-03-01 | — | — | EP | disclosed |