Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | C5 | P01031 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.42 |
| ▸ | ESRRA | P11474 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565942 | 0.90 | MCHR1 (0.54) | MCHR1 | |
| SCHEMBL6566738 | 0.89 | MCHR1 (0.45) | MCHR1BACE1BACE2MCHR2ESRRA | |
| SCHEMBL6566645 | 0.89 | KDM4E (0.53) | EPHX1HTTALDH1A1MCHR1TSHR | |
| SCHEMBL6565928 | 0.88 | MCHR1 (0.46) | MCHR1MCHR2ESRRAHPGD | |
| SCHEMBL6566565 | 0.88 | PAX8 (0.55) | HTTALDH1A1MCHR1BACE1BACE2 | |
| SCHEMBL6567876 | 0.87 | RAF1 (0.44) | HTTMCHR1ESRRA | |
| SCHEMBL6567969 | 0.87 | CASR (0.53) | MCHR1 | |
| SCHEMBL6564619 | 0.87 | MCHR1 (0.49) | MCHR1BACE1BACE2MCHR2 | |
| SCHEMBL6567939 | 0.87 | MCHR1 (0.53) | ALDH1A1MCHR1 | |
| SCHEMBL6566514 | 0.86 | MCHR1 (0.52) | MCHR1BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | EPHX1 2037/4885HTT 2150/4885ALDH1A1 907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.