Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.30 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886403 | 1.00 | BACE1 (0.32) | BACE1PPARGPPARDPPARAHDAC4 | |
| SCHEMBL6882719 | 0.89 | HDAC4 (0.32) | BACE1HDAC4HDAC6MRGPRX4 | |
| SCHEMBL6882723 | 0.89 | HDAC4 (0.32) | BACE1HDAC4HDAC6MRGPRX4 | |
| SCHEMBL6562926 | 0.89 | HDAC4 (0.32) | BACE1HDAC4HDAC6MRGPRX4 | |
| SCHEMBL6888029 | 0.88 | HDAC4 (0.31) | BACE1HDAC4HDAC6 | |
| SCHEMBL6888025 | 0.88 | HDAC4 (0.31) | BACE1HDAC4HDAC6 | |
| SCHEMBL6564641 | 0.88 | HDAC4 (0.31) | BACE1HDAC4HDAC6 | |
| SCHEMBL6882700 | 0.86 | VDR (0.43) | VDR | |
| SCHEMBL6566301 | 0.86 | VDR (0.43) | VDR | |
| SCHEMBL6882705 | 0.86 | VDR (0.43) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |
| EP-1235824-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038320-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |