Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | FYN | P06241 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27587221 | 0.90 | VDR (0.43) | VDRMAOBFYNALOX5CYP4F2 | |
| SCHEMBL6564607 | 0.86 | VDR (0.57) | VDRMAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL6562865 | 0.82 | VDR (0.61) | VDRMAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL6564158 | 0.82 | VDR (0.52) | VDR | |
| SCHEMBL6564905 | 0.80 | VDR (0.51) | VDRMAOBALOX5NR4A1NR4A2 | |
| SCHEMBL6564106 | 0.80 | VDR (0.58) | VDRMAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL7605318 | 0.78 | VDR (0.41) | VDRFYNALOX5CYP4F2CYP4A11 | |
| SCHEMBL7605313 | 0.77 | VDR (0.40) | VDRFYNALOX5CYP4F2CYP4A11 | |
| SCHEMBL6566409 | 0.77 | VDR (0.49) | VDRMAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL6564194 | 0.77 | VDR (0.50) | VDRMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |
| CN-1423627-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2003-06-11 | — | — | CN | claimed |
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| CN-1423627-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2003-06-11 | — | — | CN | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |