Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886230 | 0.88 | FFAR1 (0.48) | FFAR1NR1H4FFAR4MRGPRX4PPARD | |
| SCHEMBL6566401 | 0.83 | FFAR1 (0.51) | FFAR1NR1H4FFAR4PTPN11NR4A2 | |
| SCHEMBL7611165 | 0.79 | FFAR1 (0.47) | FFAR1NR1H4FFAR4PTPN11 | |
| SCHEMBL6564951 | 0.78 | FFAR1 (0.46) | FFAR1NR1H4FFAR4PTPN11PPARD | |
| SCHEMBL6565068 | 0.76 | FFAR1 (0.49) | FFAR1FFAR4NR4A2MRGPRX4 | |
| SCHEMBL9394690 | 0.72 | NR4A2 (0.64) | NR1H4NR4A2MRGPRX4 | |
| SCHEMBL9394698 | 0.72 | NR4A2 (0.64) | NR4A2MRGPRX4 | |
| SCHEMBL7161222 | 0.72 | MAOB (0.65) | NR4A2 | |
| SCHEMBL6889121 | 0.71 | FFAR1 (0.47) | FFAR1NR1H4FFAR4MRGPRX4PPARD | |
| SCHEMBL7179554 | 0.71 | SMN1; SMN2 (0.58) | FFAR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |