Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 16/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566401 | 0.88 | FFAR1 (0.51) | FFAR1FFAR4NR1H4VDRPPARD | |
| SCHEMBL6886230 | 0.83 | FFAR1 (0.48) | FFAR1FFAR4NR1H4PPARDMRGPRX4 | |
| SCHEMBL6563025 | 0.80 | VDR (0.58) | FFAR1FFAR4NR1H4VDRPPARD | |
| SCHEMBL6888828 | 0.78 | FFAR1 (0.43) | FFAR1FFAR4NR1H4PPARD | |
| SCHEMBL7115523 | 0.76 | FFAR1 (0.45) | FFAR1FFAR4MRGPRX4 | |
| SCHEMBL27568017 | 0.76 | VDR (0.42) | FFAR1FFAR4NR1H4VDRPPARD | |
| SCHEMBL2024484 | 0.76 | MAOB (0.58) | FFAR1PPARD | |
| SCHEMBL12641009 | 0.76 | FFAR1 (0.57) | FFAR1FFAR4PPARDMRGPRX4 | |
| SCHEMBL6562865 | 0.74 | VDR (0.61) | FFAR1FFAR4VDR | |
| SCHEMBL6564943 | 0.71 | FFAR1 (0.52) | FFAR1FFAR4NR1H4PPARDMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831106-B1 | Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-14 | — | — | US | disclosed |