Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27506741 | 0.85 | FFAR3 (0.35) | HDAC1HDAC8HDAC6LMNAPGR | |
| Acetic Acid SCHEMBL1033681 | 0.82 | FFAR3 (0.39) | HDAC1PGRADRA2AADRA2BHTR2A | |
| Propionic Acid SCHEMBL27829635 | 0.80 | FFAR3 (0.53) | HDAC1HDAC8PGRADRA2AADRA2B | |
| Carbamic Acid SCHEMBL28872525 | 0.80 | ACHE (0.37) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL28142086 | 0.77 | MEN1 (0.38) | HDAC1HDAC8HDAC6 | |
| Pivalate SCHEMBL1831109 | 0.76 | TSHR (0.33) | PGRADRA2AADRA2BHTR2AHRH1 | |
| Methyl Alcohol SCHEMBL2652388 | 0.76 | MEN1 (0.38) | — | |
| SCHEMBL7097725 | 0.76 | — | — | |
| SCHEMBL1746 | 0.76 | — | — | |
| SCHEMBL5544690 | 0.76 | MEN1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1377546-A2 | PROCESS FOR PRODUCING THIOSEMICARBAZIDES | Dow AgroSciences LLC (US) | 2004-01-07 | — | — | EP | claimed |
| WO-2002081438-A2 | PROCESS FOR PRODUCING THIOSEMICARBAZIDES | DOW AGROSCIENCES LCC (US) | 2002-10-17 | — | — | WO | claimed |
| WO-1998037074-A1 | PROCESS FOR PREPARATION OF 2-MERCAPTOTHIAZOLE | ZENECA LIMITED (GB) | 1998-08-27 | — | — | WO | claimed |
| EP-1377546-A2 | PROCESS FOR PRODUCING THIOSEMICARBAZIDES | Dow AgroSciences LLC (US) | 2004-01-07 | — | — | EP | disclosed |
| WO-2002081438-A2 | PROCESS FOR PRODUCING THIOSEMICARBAZIDES | DOW AGROSCIENCES LCC (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-1998037074-A1 | PROCESS FOR PREPARATION OF 2-MERCAPTOTHIAZOLE | ZENECA LIMITED (GB) | 1998-08-27 | — | — | WO | disclosed |