Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563741 | 0.90 | AAK1 (0.35) | PTPN11AAK1 | |
| SCHEMBL6565352 | 0.89 | PTPN11 (0.33) | PTPN11AAK1 | |
| SCHEMBL6565278 | 0.88 | PTPN11 (0.33) | PTPN11AAK1 | |
| SCHEMBL6565350 | 0.87 | HPGD (0.33) | PTPN11AAK1 | |
| SCHEMBL6565305 | 0.86 | AAK1 (0.33) | PTPN11AAK1 | |
| SCHEMBL6561938 | 0.86 | ABL1 (0.36) | DDB1CRBN | |
| SCHEMBL6563627 | 0.85 | PTPN11 (0.33) | PTPN11AAK1DDB1CRBN | |
| SCHEMBL6563932 | 0.84 | HTT (0.34) | PTPN11 | |
| SCHEMBL6563693 | 0.83 | F2 (0.40) | — | |
| SCHEMBL6563752 | 0.81 | GAA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |