Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563605 | 0.91 | GAA (0.37) | GAAALDH1A1HPGDNAMPTNPC1 | |
| SCHEMBL6563507 | 0.90 | KCNK3 (0.31) | GAAALDH1A1HPGDNAMPTNPC1 | |
| SCHEMBL6565417 | 0.90 | PTPN11 (0.36) | GAAALDH1A1HPGDNAMPTNPC1 | |
| SCHEMBL6561938 | 0.87 | ABL1 (0.36) | GAAALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL6563627 | 0.86 | PTPN11 (0.33) | — | |
| SCHEMBL6563002 | 0.85 | HRH3 (0.42) | GAAALDH1A1HPGDNAMPTNPC1 | |
| SCHEMBL6563591 | 0.85 | LRRK2 (0.39) | GAAALDH1A1HPGDNAMPTHRH3 | |
| SCHEMBL6563410 | 0.84 | GAA (0.40) | GAAALDH1A1HPGDNAMPTHSD11B1 | |
| SCHEMBL6561835 | 0.84 | PTPN11 (0.35) | GAAALDH1A1HPGDNAMPTNPC1 | |
| SCHEMBL6565309 | 0.81 | PTPN11 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |