Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.59 |
| ▸ | NQO2 | P16083 | 2/20 | 0.59 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 1/20 | 0.59 |
| ▸ | PLG | P00747 | 1/20 | 0.59 |
| ▸ | PLAT | P00750 | 1/20 | 0.59 |
| ▸ | PROC | P04070 | 1/20 | 0.59 |
| ▸ | HPN | P05981 | 1/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.59 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.59 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564395 | 0.91 | NQO2 (0.63) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6562343 | 0.86 | F2 (0.54) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6563517 | 0.80 | F2 (0.45) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6563708 | 0.79 | NQO2 (0.50) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6562387 | 0.79 | NQO2 (0.51) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6781928 | 0.75 | F2 (0.83) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL6561967 | 0.75 | F2 (0.42) | F2NQO2SLC22A2F10PLG | |
| Dabigatran SCHEMBL3573 | 0.74 | F2 (1.00) | F2NQO2SLC22A2F10PLG | |
| SCHEMBL15498525 | 0.74 | F2 (0.61) | F2NQO2SLC22A2F10PLG | |
| Dabigatran SCHEMBL30038681 | 0.74 | F2 (1.00) | F2NQO2SLC22A2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |