Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 6/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564395 | 0.88 | NQO2 (0.63) | NQO2SMN1; SMN2HSD17B10F2NR1I2 | |
| SCHEMBL6565269 | 0.84 | ALDH1A1 (0.45) | NQO2SMN1; SMN2HSD17B10F2NR1I2 | |
| SCHEMBL6565428 | 0.82 | MEN1 (0.34) | NQO2SMN1; SMN2HSD17B10F2ALDH1A1 | |
| SCHEMBL6565360 | 0.79 | F2 (0.59) | NQO2SMN1; SMN2HSD17B10F2SLC22A2 | |
| SCHEMBL6563093 | 0.77 | NQO2 (0.32) | NQO2F2ALDH1A1MAPK1MEN1 | |
| SCHEMBL6563344 | 0.75 | NQO2 (0.33) | NQO2 | |
| SCHEMBL6563537 | 0.74 | PLAU (0.38) | KMT2A | |
| SCHEMBL6565418 | 0.74 | MEN1 (0.33) | SMN1; SMN2HSD17B10F2ALDH1A1MAPK1 | |
| SCHEMBL6561955 | 0.73 | SMN1; SMN2 (0.31) | SMN1; SMN2MAPT | |
| SCHEMBL6565414 | 0.73 | PTPN11 (0.33) | NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |