Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 15/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565226 | 0.92 | ITGB3 (0.34) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL6563780 | 0.90 | EGLN1 (0.32) | — | |
| SCHEMBL6565317 | 0.86 | ITGB3 (0.33) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL6561866 | 0.85 | ITGB3 (0.37) | ITGB3ITGA2BF2 | |
| SCHEMBL6565443 | 0.83 | KCNA5 (0.31) | — | |
| SCHEMBL6565320 | 0.81 | — | — | |
| SCHEMBL6565989 | 0.80 | ITGB3 (0.36) | ITGB3ITGA2BF2PRSS1TMPRSS15 | |
| SCHEMBL6563661 | 0.79 | F2 (0.37) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL6563260 | 0.79 | F10 (0.34) | ITGB3ITGA2BF2PRSS1 | |
| SCHEMBL7677060 | 0.77 | ITGB3 (0.32) | ITGB3ITGA2BF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |
| EP-1140802-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM KG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035859-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-06-22 | — | — | WO | disclosed |