SCHEMBL6565400

SCHEMBL6565400

c1ccc(C2CCCc3ccccc3O2)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.49
ADORA3 P0DMS8 2/20 0.49
KDM4E B2RXH2 2/20 0.49
HSD17B10 Q99714 2/20 0.49
AR P10275 2/20 0.49
CYP19A1 P11511 2/20 0.49
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
TSHR P16473 1/20 0.41
SLC8A1 P32418 2/20 0.40
FFAR1 O14842 1/20 0.40
NPC1 O15118 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
MAOA P21397 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flavane SCHEMBL29478071 0.89 ESR1 (0.51) MAOBADORA3KDM4EHSD17B10AR
Flavane SCHEMBL14394530 0.89 ESR1 (0.51) MAOBADORA3KDM4EHSD17B10AR
Flavane SCHEMBL27595228 0.89 ESR1 (0.51) MAOBADORA3KDM4EHSD17B10AR
Flavane SCHEMBL27889134 0.89 ESR1 (0.51) MAOBADORA3KDM4EHSD17B10AR
Flavane SCHEMBL123287 0.89 ESR1 (0.51) MAOBADORA3KDM4EHSD17B10AR
Flavane SCHEMBL28394714 0.87 ESR1 (0.50) MAOBADORA3KDM4EHSD17B10AR
Flavane SCHEMBL28787244 0.87 ESR1 (0.50) MAOBADORA3KDM4EHSD17B10AR
Flavane SCHEMBL28405195 0.87 ESR1 (0.50) MAOBADORA3KDM4EHSD17B10AR
Flavane SCHEMBL28529260 0.87 ESR1 (0.50) MAOBADORA3KDM4EHSD17B10AR
Flavane SCHEMBL28823768 0.87 ESR1 (0.50) MAOBADORA3KDM4EHSD17B10AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1403256-A1 FUSED IMIDAZOLE DERIVATIVE FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-31 EP disclosed