Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.36 |
| ▸ | F2 | P00734 | 6/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563659 | 0.91 | ITGB3 (0.37) | ITGB3ITGA2BF2F10PLAU | |
| SCHEMBL6565268 | 0.84 | F2 (0.38) | ITGB3ITGA2BF2F10PLG | |
| SCHEMBL7677445 | 0.82 | ITGB3 (0.36) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL6563331 | 0.80 | F2 (0.43) | ITGB3ITGA2BF2 | |
| SCHEMBL6565342 | 0.79 | ITGB3 (0.38) | ITGB3ITGA2BF2F10PLG | |
| SCHEMBL6561902 | 0.78 | F2 (0.40) | ITGB3ITGA2BF2 | |
| SCHEMBL6564229 | 0.78 | F2 (0.43) | ITGB3ITGA2BF2F10PLG | |
| SCHEMBL6563705 | 0.78 | PRSS1 (0.35) | ITGB3ITGA2BF2F10PLG | |
| SCHEMBL7676372 | 0.78 | F2 (0.43) | F2 | |
| SCHEMBL4250003 | 0.77 | ITGB3 (0.37) | ITGB3ITGA2BF2F10PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |