Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27566882 | 0.91 | HPRT1 (0.47) | ANPEPCYP2A6KDM4EHSD17B10CYP1A2 | |
| SCHEMBL3478078 | 0.85 | ANPEP (0.49) | ANPEPCYP2A6KDM4EHSD17B10CYP1A2 | |
| SCHEMBL29481017 | 0.80 | ALDH1A1 (0.50) | ANPEPCYP2A6KDM4EHSD17B10CYP1A2 | |
| SCHEMBL54652 | 0.80 | ALDH1A1 (0.50) | ANPEPCYP2A6KDM4EHSD17B10CYP1A2 | |
| SCHEMBL29811500 | 0.78 | ANPEP (0.55) | ANPEPCYP2A6KDM4EHSD17B10CYP1A2 | |
| SCHEMBL2535555 | 0.78 | ANPEP (0.55) | ANPEPCYP2A6KDM4EHSD17B10CYP1A2 | |
| SCHEMBL31274510 | 0.78 | ANPEP (0.55) | ANPEPCYP2A6KDM4EHSD17B10CYP1A2 | |
| SCHEMBL27778037 | 0.77 | HPRT1 (0.47) | ANPEPCYP2A6KDM4EHSD17B10CYP1A2 | |
| SCHEMBL7631756 | 0.76 | HPRT1 (0.50) | ANPEPCYP2A6HSD17B10CYP1A2HPGD | |
| Formaldehyde SCHEMBL27966310 | 0.76 | ANPEP (0.54) | ANPEPCYP2A6KDM4EHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002053522-A2 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS I | KARO BIO AB (SE) | 2002-07-11 | — | — | WO | disclosed |
| EP-0635495-B1 | Benzospiroalkene derivates, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1998-09-16 | — | — | EP | disclosed |
| US-5648374-A | A2-ADRENERGIC AGONISTS | ADIR ET COMPAGNIE (FR) | 1997-07-15 | — | — | US | disclosed |
| US-5486532-A | ADRENERGIC AGONIST | ADIR ET COMPAGNIE (FR) | 1996-01-23 | — | — | US | disclosed |
| EP-0635495-A2 | Benzospiroalkene derivates, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-01-25 | — | — | EP | disclosed |