SCHEMBL6565635

SCHEMBL6565635

CC(=O)Oc1ccc2nc(-c3ccc4cc(-c5nc6ccc(OC(C)=O)cc6c(=O)o5)ccc4c3)oc(=O)c2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.67
MAPT P10636 6/20 0.67
ALDH1A1 P00352 4/20 0.67
LMNA P02545 2/20 0.67
KDM4E B2RXH2 5/20 0.66
GAA P10253 2/20 0.66
CD74 P04233 1/20 0.65
MIF P14174 1/20 0.65
KMT2A Q03164 4/20 0.58
PKM P14618 1/20 0.55
MEN1 O00255 2/20 0.53
TP53 P04637 2/20 0.51
HSD17B10 Q99714 1/20 0.51
NPC1 O15118 3/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
GLA P06280 2/20 0.48
GAPDH P04406 1/20 0.47
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565958 0.95 POLB (0.70) POLBMAPTALDH1A1LMNAKDM4E
SCHEMBL11104577 0.88 POLB (0.61) POLBMAPTALDH1A1LMNAKDM4E
SCHEMBL30893103 0.86 MAPT (0.69) POLBMAPTALDH1A1LMNAKDM4E
SCHEMBL18131038 0.86 MAPT (0.69) POLBMAPTALDH1A1LMNAKDM4E
SCHEMBL30893104 0.86 MAPT (0.69) POLBMAPTALDH1A1LMNAKDM4E
SCHEMBL11100686 0.85 POLB (0.58) POLBMAPTALDH1A1LMNAKDM4E
SCHEMBL6563993 0.84 MAPT (0.65) POLBMAPTALDH1A1LMNAKDM4E
SCHEMBL17254710 0.82 ALDH1A1 (0.77) POLBMAPTALDH1A1LMNAKDM4E
SCHEMBL17254733 0.82 POLB (0.55) POLBMAPTALDH1A1LMNAKDM4E
SCHEMBL6565397 0.82 KMT2A (0.50) POLBMAPTALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed