⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL87764 | 0.81 | — | — | |
| SCHEMBL5438295 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL27711738 | 0.78 | ALDH1A1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL10636902 | 0.78 | — | — | |
| Bromide SCHEMBL9820146 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL16568824 | 0.75 | ALDH1A1 (0.33) | — | |
| Propene SCHEMBL10414892 | 0.75 | — | — | |
| Cyclopropane SCHEMBL5845656 | 0.73 | ALDH1A1 (0.32) | — | |
| SCHEMBL370117 | 0.72 | TSHR (0.41) | — | |
| SCHEMBL4095968 | 0.72 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111671767-B | Proton-binding polymers for oral administration | 特里赛达公司 | 2024-03-08 | — | — | CN | claimed |
| US-9993500-B2 | Proton-binding polymers for oral administration | TRICIDA, INC. (US) | 2018-06-12 | — | — | US | claimed |
| US-9205107-B2 | Proton-binding polymers for oral administration | TRICIDA, INC. (US) | 2015-12-08 | — | — | US | claimed |
| EP-3718551-B1 | PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION | RENOSIS INC (US) | 2026-02-04 | — | — | EP | disclosed |
| EP-3812761-B1 | PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION | RENOSIS INC (US) | 2025-12-24 | — | — | EP | disclosed |
| US-20250222021-A1 | METHOD OF TREATING ACID-BASE DISORDERS | RENIBUS THERAPEUTICS, INC. | 2025-07-10 | — | — | US | disclosed |
| US-20250025494-A1 | COMPOSITIONS FOR AND METHOD OF TREATING ACID-BASE DISORDERS | RENIBUS THERAPEUTICS, INC. | 2025-01-23 | — | — | US | disclosed |
| US-20250009785-A1 | HCL-BINDING COMPOSITIONS FOR AND METHODS OF TREATING ACID-BASE DISORDERS | RENIBUS THERAPEUTICS, INC. | 2025-01-09 | — | — | US | disclosed |
| US-11992501-B2 | Compositions for and methods of treating acid-base disorders | RENOSIS, INC. (US) | 2024-05-28 | — | — | US | disclosed |
| US-11986490-B2 | Compositions for and method of treating acid-base disorders | RENOSIS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20230405043-A1 | PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION | RENIBUS THERAPEUTICS, INC. | 2023-12-21 | — | — | US | disclosed |
| CN-101175470-A | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| EP-0879840-B2 | Organopolysiloxanes containing polyhydroxyorganyl groups, especially sugar or sugar derivative groups, and polyoxyalkylene groups | GOLDSCHMIDT AG TH (DE) | 2004-03-31 | — | — | EP | disclosed |
| EP-0879840-B1 | Organopolysiloxanes containing polyhydroxyorganyl groups, especially sugar or sugar derivative groups, and polyoxyalkylene groups | GOLDSCHMIDT AG TH (DE) | 2001-03-14 | — | — | EP | disclosed |
| EP-0857065-B1 | USE OF 2-AMINO-4-(4-FLUOROBENZYLAMINO)-1-ETHOXY-CARBONYLAMINOBENZENE FOR PROPHYLAXIS AND TREATMENT OF SEQUELAE OF ACUTE AND CHRONIC REDUCED CIRCULATION IN THE BRAIN AND NEURODEGENERATIVE DISORDERS | ASTA MEDICA AG (DE) | 1999-04-07 | — | — | EP | disclosed |
| EP-0879840-A2 | Organopolysiloxanes containing polyhhydroxyorganyl groups, especially sugar or sugar derivative groups , and polyoxyalkylene groups | Th. Goldschmidt AG (DE) | 1998-11-25 | — | — | EP | disclosed |
| EP-0525782-B1 | Process for the preparation of functionalised diphenylsiloxane-dimethylsiloxane copolymers | DOW CORNING TORAY SILICONE (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5223596-A | DIPHENYSILOXANE-DIMETHYLSIOXANE COPOLYMER AND METHOD FOR THE PREPARATION THEREOF | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0525782-A1 | Process for the preparation of functionalised diphenylsiloxane-dimethylsiloxane copolymers | Dow Corning Toray Silicone Company, Limited (JP) | 1993-02-03 | — | — | EP | disclosed |
| US-5167947-A | Enhancement of absorption of radioprotective drugs | SOUTHWEST RESEARCH INSTITUTE (US) | 1992-12-01 | — | — | US | disclosed |