SCHEMBL6565739

SCHEMBL6565739

O=C1NNCC1Cc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.51
CRBN Q96SW2 1/20 0.51
HDAC8 Q9BY41 2/20 0.44
MAOB P27338 2/20 0.41
CA2 P00918 1/20 0.40
HSD11B1 P28845 1/20 0.40
GBA1 P04062 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6829791 0.75 CRBN (0.57) DDB1CRBNHDAC8MAOBCA2
SCHEMBL11627737 0.71 DDB1 (0.49) DDB1CRBNHDAC8MAOBGBA1
SCHEMBL29013938 0.71 DDB1 (0.52) DDB1CRBNHDAC8MAOBHSD11B1
SCHEMBL7268381 0.70 CRBN (0.70) DDB1CRBNHDAC8MAOBCA2
SCHEMBL837901 0.70 DDB1 (0.60) DDB1CRBNHDAC8MAOBHSD11B1
SCHEMBL17070912 0.70 EP300 (0.48) DDB1CRBNHDAC8MAOBCA2
SCHEMBL27657157 0.70 DDB1 (0.55) DDB1CRBNHDAC8MAOBHSD11B1
SCHEMBL7438778 0.69 DDB1 (0.50) DDB1CRBNHDAC8MAOBCA2
SCHEMBL7566142 0.69 MAOB (0.51) DDB1CRBNHDAC8MAOBCA2
SCHEMBL27447761 0.69 HDAC8 (0.50) DDB1CRBNHDAC8MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0896246-B1 Photographic solution for developing a silver halide photographic product EASTMAN KODAK CO (US) 2004-09-15 EP disclosed
EP-0896247-B1 Method of processing a silver halide photographic product EASTMAN KODAK CO (US) 2004-03-31 EP disclosed
EP-0802452-B1 Method for developing a photographic product with incorporated developer EASTMAN KODAK CO (US) 2002-11-06 EP disclosed
US-6218093-B1 PHOTOGRAPHIC KIT EASTMAN KODAK COMPANY 2001-04-17 US disclosed
US-5955246-A DEVELOPING SOLUTION CONTAINING AN ALKANOLAMINE IN A QUANTITY GREATER THAN OR EQUAL TO 0.6 MOL/L, AT LEAST ONE WETTING AGENT STABLE AT A HIGH PH, A DEVELOPING AGENT CAPABLE OF REDUCING SILVER IONS, AND A QUATERNARY AMMONIUM SALT EASTMAN KODAK COMPANY (US) 1999-09-21 US disclosed
EP-0896246-A1 Photographic solution for developing a silver halide photographic product EASTMAN KODAK COMPANY (US) 1999-02-10 EP disclosed
EP-0896247-A1 Method of processing a silver halide photographic product EASTMAN KODAK COMPANY (US) 1999-02-10 EP disclosed
US-5789144-A MIXTURE OF ALKANOLAMINE, WETTING AGENT AND QUATERNARYAMMONIUM COMPOUND EASTMAN KODAK COMPANY (US) 1998-08-04 US disclosed
EP-0802452-A1 Method for developing a photographic product with incorporated developer EASTMAN KODAK COMPANY (US) 1997-10-22 EP disclosed