Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566982 | 0.86 | MTOR (0.47) | KMT2ALMNAKDM4EMEN1ALDH1A1 | |
| SCHEMBL6566512 | 0.84 | MEN1 (0.44) | KMT2ALMNAKDM4EMEN1ALDH1A1 | |
| SCHEMBL6566999 | 0.82 | CASR (0.41) | KMT2ALMNAMEN1MAPTCASR | |
| SCHEMBL6564504 | 0.79 | KDM4E (0.51) | KMT2ALMNAKDM4EMEN1ALDH1A1 | |
| SCHEMBL6568022 | 0.77 | CASR (0.45) | KMT2ALMNAKDM4EMEN1ALDH1A1 | |
| SCHEMBL6568024 | 0.76 | KDM4E (0.48) | KMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL6568097 | 0.76 | CASR (0.54) | LMNAKDM4EALDH1A1CASR | |
| SCHEMBL6564738 | 0.76 | CASR (0.44) | KMT2ALMNAKDM4EMEN1MAPT | |
| SCHEMBL6564786 | 0.75 | KMT2A (0.61) | KMT2ALMNAKDM4EMEN1ALDH1A1 | |
| SCHEMBL6567065 | 0.74 | CASR (0.43) | KMT2ALMNAMEN1MAPTCASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | KMT2A 3137/4885LMNA 4043/4885KDM4E 2962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.