SCHEMBL6565871

SCHEMBL6565871

CCCc1cccc(C2c3c(C)c(N4Cc5cc(OC)c(OC)cc5C4)c(C)c(C)c3OC2(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ABCC1 P33527 1/20 0.33
DPP4 P27487 3/20 0.32
DRD2 P14416 1/20 0.31
DRD1 P21728 1/20 0.31
DRD4 P21917 1/20 0.31
DRD5 P21918 1/20 0.31
DRD3 P35462 1/20 0.31
TLR4 O00206 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2778461 0.86 KMT2A (0.36) DPP4TLR4ACHE
SCHEMBL6565862 0.84 DPP4 (0.38) DPP4ACHE
Hydrochloric Acid SCHEMBL4821106 0.83 BCHE (0.31) TLR4ACHE
SCHEMBL29567882 0.82 TLR4 (0.35) DPP4TLR4ACHE
SCHEMBL2905278 0.82 TLR4 (0.35) DPP4TLR4ACHE
SCHEMBL1269359 0.82 TLR4 (0.35) DPP4TLR4ACHE
Bromide SCHEMBL2910934 0.81 TLR4 (0.34) DPP4TLR4
Hydrochloric Acid SCHEMBL2912744 0.81 TLR4 (0.34) DPP4TLR4
SCHEMBL6565868 0.79 ABCB1 (0.32) ACHE
SCHEMBL29487577 0.79 AKT1 (0.31) TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457207-A1 SOLID COMPOSITIONS CONTAINNG COMPOUNDS UNSTABLE TO OXYGEN AND METHOD FOR STABILIZATION THEREOF Takeda Chemical Industries, Ltd. (JP) 2004-09-15 EP disclosed