SCHEMBL6566035

SCHEMBL6566035

Cc1ccc2nc(C3(c4nc5ccc(C)cc5c(=O)o4)CCCCC3)oc(=O)c2c1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.57
ALDH1A1 P00352 6/20 0.47
KDM4E B2RXH2 4/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
POLB P06746 2/20 0.47
PTK2B Q14289 1/20 0.47
C1R P00736 1/20 0.46
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
BCHE P06276 1/20 0.37
ACHE P22303 1/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565063 0.83 C1R (0.46) ELANEALDH1A1KDM4EPOLBC1R
SCHEMBL6567168 0.83 ELANE (0.37) ELANEC1R
SCHEMBL6565947 0.83 MEN1 (0.46) ELANEALDH1A1KDM4EMEN1KMT2A
SCHEMBL6564012 0.83 C1R (0.49) ALDH1A1KDM4EKMT2APOLBC1R
SCHEMBL6563999 0.83 ELANE (0.43) ELANEALDH1A1KDM4EMEN1KMT2A
SCHEMBL6564170 0.82 ALDH1A1 (0.42) ELANEALDH1A1KDM4EMEN1KMT2A
SCHEMBL6564027 0.81 IP6K1 (0.40) ELANEALDH1A1MEN1KMT2APOLB
SCHEMBL6565230 0.80 SMN1; SMN2 (0.44) ELANEALDH1A1KDM4EMEN1KMT2A
SCHEMBL6564055 0.79 APEX1 (0.49) ELANEALDH1A1MEN1KMT2APOLB
SCHEMBL6564183 0.79 KMT2A (0.54) ALDH1A1KDM4EMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed