⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566186 | 1.00 | — | — | |
| SCHEMBL6566195 | 1.00 | — | — | |
| SCHEMBL6564825 | 0.86 | CYP1A2 (0.34) | — | |
| SCHEMBL6564835 | 0.86 | CYP1A2 (0.34) | — | |
| SCHEMBL6564833 | 0.86 | CYP1A2 (0.34) | — | |
| SCHEMBL6156078 | 0.84 | PRSS1 (0.36) | — | |
| SCHEMBL6156076 | 0.84 | PRSS1 (0.36) | — | |
| SCHEMBL6156073 | 0.84 | PRSS1 (0.36) | — | |
| SCHEMBL6566284 | 0.83 | — | — | |
| SCHEMBL6564885 | 0.79 | MRGPRX4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235824-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-05-19 | — | — | EP | disclosed |
| US-6706725-B1 | BIAROMATIC COMPOUNDS WHICH ARE VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-03-16 | — | — | US | disclosed |