SCHEMBL6566239

SCHEMBL6566239

CCCCCCCCN(CCCCCCCC)c1ccccc1C(=O)c1ccccc1N(CCCCCCCC)CCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 5/20 0.50
TP53 P04637 4/20 0.50
GAA P10253 2/20 0.50
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 2/20 0.47
POLB P06746 2/20 0.47
LMNA P02545 2/20 0.46
NPC1 O15118 1/20 0.44
JAK2 O60674 1/20 0.44
RAB9A P51151 1/20 0.44
PAX8 Q06710 1/20 0.44
CYP3A4 P08684 2/20 0.44
MAPK1 P28482 1/20 0.44
ICMT O60725 1/20 0.42
ALB P02768 1/20 0.42
NAAA Q02083 1/20 0.42
MEN1 O00255 1/20 0.42
NR1I2 O75469 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567208 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT
SCHEMBL6567797 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT
SCHEMBL6566095 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT
SCHEMBL6567311 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT
SCHEMBL6568014 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT
SCHEMBL6567299 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT
SCHEMBL6569140 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT
SCHEMBL6567779 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT
SCHEMBL6568005 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT
SCHEMBL6567938 1.00 ALDH1A1 (0.50) ALDH1A1TSHRTP53GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0939102-B1 Rubber compounds containing aromatic ketone polysulfides GOODYEAR TIRE & RUBBER (US) 2004-04-07 EP disclosed
US-6303821-B1 IMPROVE THE POLYMER-FILLER INTERACTION OF ELASTOMERS OR RUBBERS. THE GOODYEAR TIRE & RUBBER COMPANY 2001-10-16 US disclosed
US-6277926-B1 PROCESSING RUBBER BY MIXING WITH A BIS-(4-AMINOPHENYL)-CARBONYL-(1,4-PHENYLENE)-POLYSUFIDE TO INCREASE THE MOONEY VISCOSITY I.E. STIFFNESS; IMPROVED POLYMER/FILLER INTERACTION; RECEPTIVITY THE GOODYEAR TIRE & RUBBER COMPANY 2001-08-21 US disclosed
US-6075096-A BIS(ALKYLAMINO)BENZOPHENONES BRIDGED TOGETHER BY A POLYSULFIDE GROUP (SX, X=2-8) WHICH ACTS TO IMPROVE THE POLYMER-FILLER INTERACTION OF ELASTOMERS OR RUBBERS; FORMED COMPOSITE PRODUCTS SUCH AS TIRES, SHOE HEELS THE GOODYEAR TIRE & RUBBER COMPANY (US) 2000-06-13 US disclosed
EP-0939102-A2 Rubber compounds containing aromatic ketone polysulfides THE GOODYEAR TIRE & RUBBER COMPANY (US) 1999-09-01 EP disclosed