SCHEMBL6566288

SCHEMBL6566288

CCC(O)c1ccc(-c2cccc(COc3ccc(CO)c(CO)c3)c2)c(C)c1

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 19/20 0.45
FFAR4 Q5NUL3 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7608281 0.91 FFAR1 (0.43) FFAR1FFAR4
SCHEMBL7606369 0.87 FFAR1 (0.43) FFAR1FFAR4
SCHEMBL6882116 0.86 VDR (0.41) FFAR1FFAR4
SCHEMBL6566293 0.86 FFAR1 (0.51) FFAR1FFAR4
SCHEMBL7611585 0.83 VDR (0.42) FFAR1FFAR4
SCHEMBL7606371 0.83 FFAR1 (0.47) FFAR1FFAR4
SCHEMBL6566235 0.80 VDR (0.43) FFAR1FFAR4
SCHEMBL6563025 0.80 VDR (0.58) FFAR1FFAR4
SCHEMBL7610502 0.79 VDR (0.42) FFAR1FFAR4
SCHEMBL7606646 0.79 FFAR1 (0.51) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1235777-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2004-06-16 EP claimed
US-6831106-B1 Selective activity on cell proliferation and differentiation without displaying any hypercalcaemiant nature GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2004-12-14 US disclosed
EP-1235777-B1 VITAMIN D ANALOGUES GALDERMA RES & DEV (FR) 2004-06-16 EP disclosed