Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.46 |
| ▸ | RXRB | P28702 | 3/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | BLVRB | P30043 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30159253 | 0.84 | NR1H4 (0.51) | RXRARXRBFOLH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2951399 | 0.84 | NR1H4 (0.51) | RXRARXRBFOLH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10598796 | 0.81 | TTR (0.52) | RXRARXRBFOLH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6888946 | 0.81 | EGFR (0.57) | ALDH1A1EGFRTSHRKDM4AKDM4E | |
| SCHEMBL25470904 | 0.81 | BCL2L1 (0.58) | ALDH1A1EGFRKDM4ELMNAHSD17B10 | |
| SCHEMBL2038730 | 0.81 | HSD17B10 (0.64) | RXRARXRBALDH1A1EGFRRARB | |
| SCHEMBL29876739 | 0.81 | HSD17B10 (0.64) | RXRARXRBALDH1A1EGFRRARB | |
| SCHEMBL31156157 | 0.81 | SRD5A2 (0.47) | RXRARXRBFOLH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2038942 | 0.81 | MAP4K4 (0.46) | RXRARXRBFOLH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28188905 | 0.81 | TTR (0.61) | RXRARXRBFOLH1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | disclosed |