Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 3/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562954 | 0.91 | VDR (0.57) | VDRLMNAPOLBRAB9AATM | |
| SCHEMBL6566493 | 0.85 | VDR (0.51) | VDRLMNAPOLBRAB9AATM | |
| SCHEMBL6563004 | 0.85 | VDR (0.51) | VDRESR2ESR1 | |
| SCHEMBL6566504 | 0.82 | VDR (0.50) | VDR | |
| SCHEMBL6564145 | 0.82 | VDR (0.55) | VDRMAOB | |
| SCHEMBL6563023 | 0.81 | VDR (0.61) | VDRESR2 | |
| SCHEMBL6563025 | 0.77 | VDR (0.58) | VDRFFAR1 | |
| SCHEMBL6564192 | 0.77 | VDR (0.68) | VDRLMNAMAOBFFAR1 | |
| SCHEMBL6562993 | 0.76 | VDR (0.65) | VDRMAOBFFAR1 | |
| SCHEMBL6563016 | 0.76 | VDR (0.80) | VDRMAOBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | disclosed |