Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.47 |
| ▸ | VDR | P11473 | 3/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605149 | 0.85 | FFAR1 (0.53) | FFAR1VDRNR1H2NR1H3 | |
| SCHEMBL7605154 | 0.83 | FFAR1 (0.50) | FFAR1VDRNR1H2NR1H3 | |
| SCHEMBL6564106 | 0.79 | VDR (0.58) | FFAR1VDRNR1H2NR1H3 | |
| SCHEMBL6565081 | 0.76 | VDR (0.43) | FFAR1VDR | |
| SCHEMBL6566235 | 0.76 | VDR (0.43) | FFAR1VDRPTGS2 | |
| SCHEMBL7610474 | 0.73 | VDR (0.38) | FFAR1VDRPTGS2 | |
| SCHEMBL7611585 | 0.73 | VDR (0.42) | FFAR1VDRPTGS2 | |
| SCHEMBL7610502 | 0.73 | VDR (0.42) | FFAR1VDRPTGS2 | |
| SCHEMBL7608820 | 0.73 | VDR (0.43) | FFAR1VDR | |
| SCHEMBL2495554 | 0.72 | FFAR1 (0.48) | FFAR1PTGS2NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |