Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566542 | 0.88 | HTR1A (0.71) | HTR1AALDH1A1LMNADRD4KDM4E | |
| SCHEMBL7700763 | 0.87 | HTR1A (0.70) | HTR1AMEN1KMT2AL3MBTL1HTR6 | |
| SCHEMBL7703235 | 0.81 | HTR1A (0.60) | HTR1AMEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL6567496 | 0.81 | HTR1A (0.60) | HTR1AMEN1RECQLKMT2AKDM4E | |
| SCHEMBL7704555 | 0.81 | HTR1A (0.59) | HTR1AMEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL7704512 | 0.79 | HTR1A (0.57) | HTR1AMEN1RECQLKMT2AHTR6 | |
| SCHEMBL7698829 | 0.79 | HTR1A (0.57) | HTR1AMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL6565627 | 0.78 | HTR1A (0.55) | HTR1AMEN1RECQLKMT2AALDH1A1 | |
| SCHEMBL6565630 | 0.77 | HTR1A (0.55) | HTR1AMEN1RECQLKMT2AL3MBTL1 | |
| SCHEMBL7701352 | 0.77 | HTR1A (0.55) | HTR1ARECQLALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1135360-B1 | NOVEL 3-ALKOXYBENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICINES FOR TREATING SCHIZOPHRENIA | PF MEDICAMENT (FR) | 2004-03-31 | — | — | EP | claimed |
| US-6350913-B1 | AROMATIC AMINE COMPOUNDS | PIERRE FABRE MEDICAMENT (FR) | 2002-02-26 | — | — | US | claimed |
| EP-1135360-A1 | NOVEL 3-ALKOXYBENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICINES FOR TREATING SCHIZOPHRENIA | PIERRE FABRE MEDICAMENT (FR) | 2001-09-26 | — | — | EP | claimed |
| WO-2000032557-A1 | NOVEL 3-ALKOXYBENZYLAMINE DERIVATIVES AND THEIR USE AS MEDICINES FOR TREATING SCHIZOPHRENIA | PIERRE FABRE MEDICAMENT (FR) | 2000-06-08 | — | — | WO | claimed |