Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 19/20 | 0.58 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.55 |
| ▸ | IDH2 | P48735 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4604152 | 0.89 | CXCR2 (0.67) | CXCR2CX3CR1 | |
| SCHEMBL6562616 | 0.85 | CXCR2 (0.66) | CXCR2CX3CR1 | |
| SCHEMBL4587287 | 0.81 | CXCR2 (0.54) | CXCR2CX3CR1IDH2 | |
| Hydrochloric Acid SCHEMBL7508535 | 0.80 | CXCR2 (0.54) | CXCR2CX3CR1 | |
| SCHEMBL6565738 | 0.80 | KMT2A (0.48) | — | |
| SCHEMBL6565908 | 0.78 | MEN1 (0.46) | — | |
| SCHEMBL6564188 | 0.77 | NPC1 (0.58) | CXCR2CX3CR1 | |
| SCHEMBL7114367 | 0.76 | CXCR2 (0.69) | CXCR2CX3CR1 | |
| SCHEMBL7502166 | 0.76 | CXCR2 (0.47) | CXCR2CX3CR1 | |
| SCHEMBL6565974 | 0.75 | KMT2A (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161232-B1 | HYDROXY DIPHENYL UREA SULFONAMIDES AS IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-03-24 | — | — | EP | disclosed |