Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.69 |
| ▸ | CXCR1 | P25024 | 7/20 | 0.69 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562438 | 0.96 | CXCR2 (0.67) | CXCR2CXCR1CX3CR1 | |
| SCHEMBL4587287 | 0.90 | CXCR2 (0.54) | CXCR2CXCR1CX3CR1 | |
| SCHEMBL4604152 | 0.85 | CXCR2 (0.67) | CXCR2CX3CR1 | |
| SCHEMBL6564188 | 0.85 | NPC1 (0.58) | CXCR2CXCR1CX3CR1 | |
| SCHEMBL4586038 | 0.84 | CXCR2 (0.65) | CXCR2CXCR1CX3CR1 | |
| SCHEMBL6562339 | 0.84 | CXCR2 (0.76) | CXCR2CXCR1CX3CR1 | |
| SCHEMBL6550665 | 0.82 | CXCR2 (1.00) | CXCR2CXCR1CX3CR1 | |
| SCHEMBL6562616 | 0.81 | CXCR2 (0.66) | CXCR2CX3CR1 | |
| SCHEMBL4587197 | 0.81 | CXCR2 (0.71) | CXCR2CXCR1CX3CR1 | |
| SCHEMBL6562813 | 0.81 | CXCR2 (0.71) | CXCR2CXCR1CX3CR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030109527-A1 | Hydroxy diphenyl urea sulfonamides as IL-8 receptor antagonists | SMITHKLINE BEECHAM CORPORATION | 2003-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109527-A1 | Hydroxy diphenyl urea sulfonamides as IL-8 receptor antagonists | CXCL8, CCR8, IL18 | CXCR2 26/4885CXCR1 18/4885CX3CR1 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.