Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857595 | 0.91 | VDR (0.74) | VDRFFAR1S1PR1S1PR5PRKD3 | |
| SCHEMBL27568064 | 0.90 | VDR (0.51) | VDRFFAR1PPARD | |
| SCHEMBL6564192 | 0.90 | VDR (0.68) | VDRFFAR1PPARDS1PR1S1PR5 | |
| SCHEMBL6564524 | 0.88 | VDR (0.47) | VDRFFAR1PPARDS1PR1S1PR5 | |
| SCHEMBL6564164 | 0.87 | VDR (0.77) | VDRFFAR1PPARDS1PR1S1PR5 | |
| SCHEMBL2641441 | 0.85 | VDR (0.84) | VDRFFAR1PPARDS1PR1S1PR5 | |
| SCHEMBL6566261 | 0.85 | VDR (0.63) | VDRFFAR1MAOB | |
| SCHEMBL27587368 | 0.85 | VDR (0.44) | VDRFFAR1PPARD | |
| SCHEMBL6564928 | 0.85 | VDR (0.64) | VDRFFAR1PPARDS1PR1S1PR5 | |
| SCHEMBL6563016 | 0.83 | VDR (0.80) | VDRFFAR1S1PR1S1PR5PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235777-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2004-06-16 | — | — | EP | claimed |
| EP-1235777-A2 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2002-09-04 | — | — | EP | claimed |
| WO-2001038303-A2 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2001-05-31 | — | — | WO | claimed |