Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15577722 | 1.00 | ALDH1A1 (0.81) | ALDH1A1MAPK1TSHRLMNAHPGD | |
| SCHEMBL12672469 | 0.92 | ALDH1A1 (0.96) | ALDH1A1MAPK1TSHRLMNAHPGD | |
| SCHEMBL6567085 | 0.90 | MAPK1 (0.81) | ALDH1A1MAPK1TSHRLMNAHPGD | |
| SCHEMBL12640166 | 0.90 | ALDH1A1 (1.00) | ALDH1A1MAPK1TSHRLMNAHPGD | |
| SCHEMBL7350215 | 0.87 | MAPK1 (0.66) | ALDH1A1MAPK1TSHRLMNAHPGD | |
| SCHEMBL6566887 | 0.85 | ALDH1A1 (0.83) | ALDH1A1MAPK1TSHRLMNAHPGD | |
| SCHEMBL15522663 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPK1TSHRLMNAHPGD | |
| SCHEMBL28001097 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPK1TSHRLMNAHPGD | |
| SCHEMBL20090510 | 0.84 | ALDH1A1 (0.62) | ALDH1A1MAPK1TSHRLMNAHPGD | |
| SCHEMBL18671536 | 0.84 | ALDH1A1 (0.81) | ALDH1A1MAPK1TSHRLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443041-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |