SCHEMBL6566913

SCHEMBL6566913

CC(=O)Nc1cc(Cl)c(O)c(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
ALDH1A1 P00352 4/20 0.55
GAA P10253 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
DHODH Q02127 1/20 0.53
RORC P51449 3/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
MAPT P10636 2/20 0.48
CA12 O43570 1/20 0.48
BRD4 O60885 1/20 0.48
NR1I2 O75469 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
MB P02144 1/20 0.48
CYP1A1 P04798 1/20 0.48
CA3 P07451 1/20 0.48
CYP3A4 P08684 1/20 0.48
RARG P13631 1/20 0.48
TSHR P16473 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11431434 0.88 LMNA (0.52) LMNAALDH1A1GAATDP1DHODH
SCHEMBL10882803 0.87 LMNA (0.50) LMNAALDH1A1GAATDP1DHODH
SCHEMBL6815028 0.86 GAA (0.60) LMNAALDH1A1GAAMEN1KMT2A
SCHEMBL20535682 0.84 LMNA (0.56) LMNAALDH1A1GAATDP1RORC
SCHEMBL12332367 0.83 LMNA (0.54) LMNAALDH1A1GAATDP1RORC
SCHEMBL6567241 0.82 EPHX1 (0.59) LMNAALDH1A1GAADHODHMEN1
SCHEMBL14606822 0.81 GAA (0.46) LMNAALDH1A1GAATDP1DHODH
SCHEMBL13602356 0.81 LMNA (0.52) LMNAALDH1A1GAATDP1RORC
SCHEMBL7139219 0.81 LMNA (0.52) LMNAALDH1A1GAATDP1RORC
SCHEMBL10824312 0.81 LMNA (0.52) LMNAALDH1A1GAATDP1RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1402887-A1 New compounds for the inhibition of undesired cell proliferation and use thereof Jerini AG (DE) 2004-03-31 EP claimed
EP-1402888-A1 The use of substituted carbocyclic compounds as rotamases inhibitors Jerini AG (DE) 2004-03-31 EP claimed
EP-0684473-B1 Immunoassay elements comprising polymers containing vanadium IV (V (+4)) ions JOHNSON & JOHNSON CLIN DIAG (US) 2001-11-07 EP claimed
EP-0684473-A2 Immunoassay elements comprising polymers containing vanadium IV (V (+4)) ions Johnson & Johnson Clinical Diagnostics, Inc. (US) 1995-11-29 EP claimed
CN-122010760-A Paracetamol disinfection by-product and preparation method and application thereof 辽宁大学 2026-05-12 CN disclosed
US-9929348-B2 Organic semiconductor composition comprising organic semiconductor material and polymer compound FUJIFILM CORPORATION (JP) 2018-03-27 US disclosed
US-9343594-B2 Conductive composition, conductive member and production method thereof, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-9343594-B2 Conductive composition, conductive member and production method thereof, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2016-05-17 US disclosed
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
US-20160064674-A1 ORGANIC SEMICONDUCTOR COMOSITION, ORGANIC THIN-FILM TRANSISTOR, ELECTRONIC PAPER, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-03-03 US disclosed
US-9224518-B2 Conductive composition, conductive member, conductive member production method, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2015-12-29 US disclosed
US-9224518-B2 Conductive composition, conductive member, conductive member production method, touch panel, and solar cell FUJIFILM CORPORATION (JP) 2015-12-29 US disclosed
EP-0589018-A1 AMINES AS INHIBITORS OF SQUALENE SYNTHASE ZENECA LIMITED (GB) 1994-03-30 EP disclosed
US-5260474-A Fungicides BAYER AKTIENGESELLSCHAFT (DE) 1993-11-09 US disclosed
WO-1993020807-A1 AMINES AS INHIBITORS OF SQUALENE SYNTHASE ZENECA LIMITED (GB) 1993-10-28 WO disclosed
EP-0293718-B1 SUBSTITUTED AMINOPHENYL CARBAMATE BAYER AG (DE) 1993-02-03 EP disclosed
US-4939170-A Substituted aminophenyl carbamates BAYER AKTIENGESELLSCHAFT (DE) 1990-07-03 US disclosed
EP-0293718-A2 Substituted aminophenyl carbamate BAYER AG (DE) 1988-12-07 EP disclosed
EP-0033583-B1 DYESTUFFS COMPRISING TWO 5-MEMBERED HETEROCYCLIC NUCLEI FUSED TO A CENTRAL CYCLOHEXADIENE NUCLEUS, PROCESSES FOR THEIR PREPARATION AND THEIR USE FOR COLOURING SYNTHETIC TEXTILE MATERIALS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-10-12 EP disclosed
EP-0033583-A1 Dyestuffs comprising two 5-membered heterocyclic nuclei fused to a central cyclohexadiene nucleus, processes for their preparation and their use for colouring synthetic textile materials IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-08-12 EP disclosed