Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132700 | 0.87 | HTT (0.51) | FFAR1HTTPLA2G4BNPC1RAB9A | |
| SCHEMBL99313 | 0.86 | FFAR1 (0.57) | FFAR1HTTPLA2G4BNPC1RAB9A | |
| SCHEMBL6568585 | 0.83 | RXRA (0.45) | FFAR1PLA2G4BNPC1RAB9APOLB | |
| SCHEMBL10072105 | 0.83 | HTT (0.50) | FFAR1HTTPLA2G4BNPC1RAB9A | |
| SCHEMBL11543183 | 0.82 | HTT (0.50) | FFAR1HTTPLA2G4BNPC1RAB9A | |
| SCHEMBL130309 | 0.82 | KMT2A (0.49) | HTTPLA2G4BNPC1RAB9APOLB | |
| SCHEMBL4706402 | 0.81 | HTT (0.56) | FFAR1HTTPLA2G4BNPC1RAB9A | |
| SCHEMBL1987313 | 0.81 | TSHR (0.52) | HTTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL132139 | 0.81 | NPC1 (0.46) | HTTPLA2G4BNPC1RAB9APOLB | |
| SCHEMBL127562 | 0.80 | PLA2G4B (0.47) | HTTPLA2G4BF2RL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1277748-B1 | Process for producing optically active y-Butyrolactone | TAKASAGO PERFUMERY CO LTD (JP) | 2004-04-21 | — | — | EP | disclosed |
| EP-1403262-A1 | Process for producing optically active alpha butyrolactone | Takasago International Corporation (JP) | 2004-03-31 | — | — | EP | disclosed |
| EP-1277748-A1 | Process for producing optically active y-Butyrolactone | Takasago International Corporation (JP) | 2003-01-22 | — | — | EP | disclosed |