SCHEMBL6567126

SCHEMBL6567126

CC(C)(C)c1cccc(Oc2cccc(C(NCC(O)C(F)(F)F)c3cccc(C(F)(F)C(F)(F)F)c3)c2)c1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CETP P11597 14/20 0.43
AOC3 Q16853 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5672299 1.00 CETP (0.43) CETPAOC3
SCHEMBL5670346 0.95 CETP (0.41) CETPAOC3
SCHEMBL6568915 0.95 CETP (0.41) CETPAOC3
SCHEMBL5670075 0.94 CETP (0.42) CETPAOC3
SCHEMBL6570046 0.94 CETP (0.42) CETPAOC3
SCHEMBL5668806 0.92 CETP (0.41) CETP
SCHEMBL6823366 0.91 CETP (0.43) CETPAOC3
SCHEMBL1900758 0.91 CETP (0.39) CETP
SCHEMBL13837709 0.91 CETP (0.39) CETP
SCHEMBL5669370 0.91 CETP (0.43) CETPAOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469831-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS Pfizer Products Inc. (US) 2004-10-27 EP disclosed
EP-1401399-A2 PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES Pfizer Products Inc. (US) 2004-03-31 EP disclosed
WO-2003063832-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A SOLID AMORPHOUS DISPERSION OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS PFIZER PRODUCTS INC. (US) 2003-08-07 WO disclosed
WO-2003000226-A2 PHARMACEUTICAL COMPOSITIONS CONTAINING POLYMER AND DRUG ASSEMBLIES PFIZER PRODUCTS INC. (US) 2003-01-03 WO disclosed