Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 13/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5669370 | 1.00 | CETP (0.43) | CETPPPARGKIF11AOC3 | |
| SCHEMBL6064717 | 0.94 | CETP (0.42) | CETPPPARGAOC3 | |
| SCHEMBL6231524 | 0.94 | CETP (0.42) | CETPPPARGAOC3 | |
| SCHEMBL5670346 | 0.93 | CETP (0.41) | CETPAOC3 | |
| SCHEMBL6568915 | 0.93 | CETP (0.41) | CETPAOC3 | |
| SCHEMBL992083 | 0.91 | CETP (0.43) | CETP | |
| SCHEMBL6280371 | 0.91 | CETP (0.43) | CETP | |
| SCHEMBL6274573 | 0.91 | CETP (0.40) | CETPAOC3 | |
| SCHEMBL5672299 | 0.91 | CETP (0.43) | CETPAOC3 | |
| SCHEMBL6567126 | 0.91 | CETP (0.43) | CETPAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401503-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING A SOLID DISPERSION OF A POORLY-SOLUBLE DRUG IN A MATRIX AND A SOLUBILITY-ENHANCING POLYMER | Pfizer Products Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003000294-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING A SOLID DISPERSION OF A POORLY-SOLUBLE DRUG IN A MATRIX AND A SOLUBILITY-ENHANCING POLYMER | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | disclosed |