Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.95 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.60 |
| ▸ | ABAT | P80404 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | JAK1 | P23458 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27516217 | 0.97 | AKT1 (1.00) | AKT1ALDH5A1ABATALDH1A1MAPK1 | |
| SCHEMBL38134 | 0.97 | AKT1 (1.00) | AKT1ALDH5A1ABATALDH1A1MAPK1 | |
| Ethylene SCHEMBL27565387 | 0.95 | AKT1 (0.95) | AKT1ALDH5A1ABATALDH1A1MAPK1 | |
| Methane SCHEMBL27566869 | 0.95 | AKT1 (0.95) | AKT1ALDH5A1ABATALDH1A1MAPK1 | |
| Formaldehyde SCHEMBL27801880 | 0.95 | AKT1 (0.95) | AKT1ALDH5A1ABATALDH1A1MAPK1 | |
| Fluoride SCHEMBL27784734 | 0.95 | AKT1 (0.95) | AKT1ALDH5A1ABATALDH1A1MAPK1 | |
| Oxalic Acid SCHEMBL27825778 | 0.93 | AKT1 (0.91) | AKT1ALDH5A1ABATALDH1A1MAPK1 | |
| SCHEMBL2768988 | 0.91 | AKT1 (0.86) | AKT1ALDH5A1ABATALDH1A1MAPK1 | |
| SCHEMBL39634 | 0.89 | AKT1 (0.83) | AKT1ALDH5A1ABATALDH1A1MAPK1 | |
| SCHEMBL28017333 | 0.87 | AKT1 (0.79) | AKT1ALDH5A1ABATALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |