SCHEMBL39634

SCHEMBL39634

C=CC(=O)c1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKT1 P31749 1/20 0.83
ALDH1A1 P00352 4/20 0.61
ALDH5A1 P51649 1/20 0.59
ABAT P80404 1/20 0.59
SRD5A2 P31213 2/20 0.58
MEN1 O00255 4/20 0.55
KMT2A Q03164 4/20 0.55
TDP1 Q9NUW8 3/20 0.55
HPGD P15428 3/20 0.55
MAPK1 P28482 2/20 0.55
MAPT P10636 2/20 0.55
KDM4E B2RXH2 1/20 0.55
EGFR P00533 1/20 0.55
TP53 P04637 1/20 0.55
CYP3A4 P08684 1/20 0.55
PKM P14618 1/20 0.55
ALOX15 P16050 1/20 0.55
ALOX12 P18054 1/20 0.55
JAK1 P23458 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27516217 0.91 AKT1 (1.00) AKT1ALDH1A1ALDH5A1ABATMEN1
SCHEMBL10772833 0.91 ALDH5A1 (0.70) AKT1ALDH1A1ALDH5A1ABATSRD5A2
SCHEMBL38134 0.91 AKT1 (1.00) AKT1ALDH1A1ALDH5A1ABATMEN1
Fluoride SCHEMBL27784734 0.89 AKT1 (0.95) AKT1ALDH1A1ALDH5A1ABATMEN1
Methane SCHEMBL27566869 0.89 AKT1 (0.95) AKT1ALDH1A1ALDH5A1ABATMEN1
Ethylene SCHEMBL27565387 0.89 AKT1 (0.95) AKT1ALDH1A1ALDH5A1ABATMEN1
Ammonia Solution, Strong SCHEMBL6567239 0.89 AKT1 (0.95) AKT1ALDH1A1ALDH5A1ABATMEN1
Formaldehyde SCHEMBL27801880 0.89 AKT1 (0.95) AKT1ALDH1A1ALDH5A1ABATMEN1
Oxalic Acid SCHEMBL27825778 0.86 AKT1 (0.91) AKT1ALDH1A1ALDH5A1ABATMEN1
SCHEMBL2768988 0.84 AKT1 (0.86) AKT1ALDH1A1ALDH5A1ABATMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117838915-A Drug sustained-release wound dressing based on natural hydrogel and preparation method thereof 四川大学 2024-04-09 CN claimed
CN-114701221-A Oriented liquid guiding composite fiber membrane with temperature adaptability and preparation method thereof 华侨大学 2022-07-05 CN claimed
CN-117838915-A Drug sustained-release wound dressing based on natural hydrogel and preparation method thereof 四川大学 2024-04-09 CN disclosed
CN-117838915-A Drug sustained-release wound dressing based on natural hydrogel and preparation method thereof 四川大学 2024-04-09 CN disclosed
CN-117756979-A Water-soluble macromolecule modified diphenyl ketone photoinitiator and preparation method thereof 南昌航空大学 2024-03-26 CN disclosed
US-20240093068-A1 ADHESIVE WITH THERMALLY REVERSIBLE, COVALENT CROSSLINKS 3M INNOVATIVE PROPERTIES COMPANY 2024-03-21 US disclosed
CN-114891302-A Ultraviolet irradiation crosslinking halogen-free flame-retardant ethylene propylene rubber cable material and cable insulating layer or sheath layer manufactured by using UV-LED 焦作铁路电缆有限责任公司 2022-08-12 CN disclosed
CN-114701221-A Oriented liquid guiding composite fiber membrane with temperature adaptability and preparation method thereof 华侨大学 2022-07-05 CN disclosed
US-10927064-B2 Process for the manufacturing of a compound comprising a (meth)acryloyl group 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-02-23 US disclosed
US-20200369590-A1 PROCESS FOR THE MANUFACTURING OF A COMPOUND COMPRISING A (METH)ACRYLOYL GROUP 3M INNOVATIVE PROPERTIES COMPANY 2020-11-26 US disclosed
EP-3502090-B1 PROCESS FOR THE MANUFACTURING OF A COMPOUND COMPRISING A (METH)ACRYLOYL GROUP 3M INNOVATIVE PROPERTIES CO (US) 2020-08-19 EP disclosed
US-8304920-B2 Energy ray-curable polymer, an energy ray-curable adhesive composition, an adhesive sheet and a processing method of a semiconductor wafer LINTEC CORPORATION (JP) 2012-11-06 US disclosed
WO-2011160636-A2 GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011160636-A2 GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011160640-A2 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011160640-A2 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
US-20110104874-A1 Energy Ray-Curable Polymer, an Energy Ray-Curable Adhesive Composition, an Adhesive Sheet and a Processing Method of a Semiconductor Wafer LINTEC CORPORATION (JP) 2011-05-05 US disclosed
US-20100233868-A1 Adhesive Sheet and a Processing Method of Semiconductor Wafer, and a Manufacturing Method of Semiconductive Chip LINTEC CORPORATION (JP) 2010-09-16 US disclosed
CN-101346400-A Method of free radically polymerizing vinyl monomers 3M INNOVATIVE PROPERTIES CO (US) 2009-01-14 CN disclosed
CN-101297011-A Mixed binder composition curable simultaneously 3M INNOVATIVE PROPERTIES CO (US) 2008-10-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927064-B2 Process for the manufacturing of a compound comprising a (meth)acryloyl group ADH5, ALKBH3, METTL3 AKT1 1633/4885ALDH1A1 138/4885ALDH5A1 1170/4885
US-20200369590-A1 PROCESS FOR THE MANUFACTURING OF A COMPOUND COMPRISING A (METH)ACRYLOYL GROUP ADH5, ALKBH3, METTL3 AKT1 1633/4885ALDH1A1 138/4885ALDH5A1 1170/4885
US-20240093068-A1 ADHESIVE WITH THERMALLY REVERSIBLE, COVALENT CROSSLINKS ICAM1, CDH1, SMC1A AKT1 3076/4885ALDH1A1 200/4885ALDH5A1 1951/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.