Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27973372 | 0.85 | CNR2 (0.41) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL7335409 | 0.85 | CTSC (0.42) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL7335419 | 0.85 | CTSC (0.42) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL7335426 | 0.85 | CTSC (0.42) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL7335416 | 0.85 | CTSC (0.42) | MAPTALOX15HTTHBBMCL1 | |
| SCHEMBL10860742 | 0.83 | CYP1A2 (0.58) | ALOX15CES1CES2CPB1CYP2C19 | |
| SCHEMBL5755300 | 0.79 | CYP1A2 (0.58) | ALOX15CPB1CYP2C19 | |
| SCHEMBL168919 | 0.78 | ELANE (0.54) | MCL1CYP3A4CYP2C19 | |
| SCHEMBL20482434 | 0.78 | ELANE (0.54) | MCL1CYP3A4CYP2C19 | |
| SCHEMBL20482162 | 0.78 | ELANE (0.54) | MCL1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200901-A | Aziridine-2-yl- (aryl) ketone derivative and preparation method thereof | 上海应用技术大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-108640949-A | A kind of DOPO- phthalimides analog derivative, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2018-10-12 | — | — | CN | disclosed |
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |