Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4357793 | 0.86 | EPHX2 (0.70) | EPHX2 | |
| SCHEMBL6565549 | 0.80 | EPHX2 (1.00) | EPHX2MAPTNPSR1 | |
| SCHEMBL25684474 | 0.79 | EPHX2 (0.84) | EPHX2LMNA | |
| SCHEMBL6566257 | 0.76 | EPHX2 (0.71) | EPHX2MAPTNPSR1 | |
| SCHEMBL4354504 | 0.76 | EPHX2 (0.67) | EPHX2MAPTNPSR1 | |
| SCHEMBL4350925 | 0.73 | EPHX2 (0.67) | EPHX2MAPTNPSR1 | |
| SCHEMBL12932207 | 0.73 | MAPT (0.68) | EPHX2MAPTNPSR1 | |
| SCHEMBL6568669 | 0.73 | EPHX2 (0.80) | EPHX2 | |
| SCHEMBL4348756 | 0.73 | NPSR1 (0.55) | EPHX2LMNAMAPTNPSR1 | |
| SCHEMBL18423981 | 0.72 | EPHX2 (1.00) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |