SCHEMBL6567250

SCHEMBL6567250

O=c1oc(-c2ccc(-c3nc4cc(Cl)ccc4c(=O)o3)cc2)nc2cc(Cl)ccc12

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.63
ALDH1A1 P00352 7/20 0.61
KDM4E B2RXH2 6/20 0.61
HPGD P15428 3/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
ELANE P08246 2/20 0.59
MAPT P10636 4/20 0.56
POLB P06746 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
NPC1 O15118 5/20 0.53
RAB9A P51151 4/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
LMNA P02545 2/20 0.53
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
RXFP1 Q9HBX9 1/20 0.53
C1R P00736 4/20 0.52
CASP3 P42574 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565952 0.92 APEX1 (0.59) APEX1ALDH1A1KDM4EHPGDMEN1
SCHEMBL914337 0.89 APEX1 (0.53) APEX1ALDH1A1KDM4EHPGDMEN1
SCHEMBL10275908 0.89 APEX1 (0.56) APEX1ALDH1A1KDM4EHPGDMEN1
SCHEMBL913296 0.89 ALDH1A1 (0.55) APEX1ALDH1A1KDM4EHPGDMEN1
SCHEMBL914201 0.88 MEN1 (0.68) APEX1ALDH1A1KDM4EHPGDMEN1
SCHEMBL2328301 0.87 ALDH1A1 (0.63) APEX1ALDH1A1KDM4EHPGDMEN1
SCHEMBL916042 0.83 PBRM1 (0.63) APEX1ALDH1A1KDM4EHPGDMEN1
SCHEMBL914144 0.83 APEX1 (0.56) APEX1ALDH1A1KDM4EHPGDMEN1
SCHEMBL14417719 0.83 ALDH1A1 (0.66) APEX1ALDH1A1KDM4EHPGDMEN1
SCHEMBL913800 0.83 APEX1 (0.67) APEX1ALDH1A1KDM4EHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711803-B1 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LTD (JP) 2000-01-19 EP claimed
US-5651926-A SYNERGISTIC SUPPRESSION WITH CYCLIC IMINO ESTERS AND QUINOXALINES TEIJIN LIMITED (JP) 1997-07-29 US claimed
EP-0711803-A2 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LIMITED (JP) 1996-05-15 EP claimed
EP-0993965-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2004-03-31 EP disclosed
US-6440897-B1 BIS-BENZOXAZINONE COMPOUND AS AN ULTRAVIOLET RAY ABSORBING AGENT NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-08-27 US disclosed
EP-0993965-A2 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-04-19 EP disclosed
EP-0711803-B1 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LTD (JP) 2000-01-19 EP disclosed
US-5651926-A SYNERGISTIC SUPPRESSION WITH CYCLIC IMINO ESTERS AND QUINOXALINES TEIJIN LIMITED (JP) 1997-07-29 US disclosed
EP-0711803-A2 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LIMITED (JP) 1996-05-15 EP disclosed