SCHEMBL6567451

SCHEMBL6567451

CCc1ccc2c(c1)OCC(=O)CO2

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.57
CMA1 P23946 1/20 0.45
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
MAPT P10636 3/20 0.43
USP2 O75604 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CYP3A4 P08684 4/20 0.42
RAB9A P51151 1/20 0.41
TAAR1 Q96RJ0 3/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
ALDH1A1 P00352 2/20 0.41
GAA P10253 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAOA P21397 1/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1292060 0.86 TAAR1 (0.46) PARP1CMA1KMT2AMEN1CYP3A4
SCHEMBL6570432 0.83 TAAR1 (0.44) PARP1CMA1TAAR1
SCHEMBL5386460 0.82 TAAR1 (0.46) PARP1CMA1MAPTNPSR1CYP3A4
SCHEMBL1292108 0.82 ALOX5 (0.46) KMT2AMEN1TAAR1
SCHEMBL20165797 0.81 TAAR1 (0.53) CMA1MAPTNPSR1CYP3A4TAAR1
SCHEMBL5372803 0.80 ALOX5 (0.48) CYP3A4TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL5381801 0.80 TAAR1 (0.49) PARP1CMA1MAPTNPSR1CYP3A4
SCHEMBL5385068 0.80 ALOX5 (0.48) CYP3A4TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL92784 0.80 TAAR1 (0.60) CMA1KMT2AMEN1MAPTCYP3A4
SCHEMBL92786 0.80 MEN1 (0.53) PARP1KMT2AMEN1MAPTUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4084769-A1 PERFUME SYSTEM FOR PERFUMED CONSUMER PRODUCT Firmenich SA (CH) 2022-11-09 EP disclosed
WO-2021214205-A1 PERFUME SYSTEM FOR PERFUMED CONSUMER PRODUCT FIRMENICH SA (CH) 2021-10-28 WO disclosed
EP-1405851-A1 Method for producing seven-membered diether compounds and intermediates thereof Takasago International Corporation (JP) 2004-04-07 EP disclosed