Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 5/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 6/20 | 0.48 |
| ▸ | FNTB | P49356 | 6/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657564 | 0.85 | FNTA (0.61) | FNTAFNTBKDM4E | |
| SCHEMBL29007522 | 0.78 | ABCC1 (0.62) | ABCB1ABCC1KCNMA1APP | |
| SCHEMBL658063 | 0.74 | FNTA (0.58) | FNTAFNTBKDM4ERECQL | |
| SCHEMBL17457463 | 0.73 | ABCB1 (0.69) | ABCB1ABCC1KCNMA1APP | |
| SCHEMBL17457465 | 0.73 | ABCB1 (0.69) | ABCB1ABCC1KCNMA1APP | |
| SCHEMBL657106 | 0.73 | KDM4E (0.59) | FNTAFNTBKDM4ERECQL | |
| SCHEMBL658338 | 0.73 | POLB (0.62) | KCNMA1FNTAFNTBKDM4ERECQL | |
| SCHEMBL20537733 | 0.71 | APP (0.63) | KCNMA1APPKDM4E | |
| SCHEMBL2645986 | 0.71 | ABCB1 (0.66) | ABCB1ABCC1KCNMA1KDM4E | |
| SCHEMBL17356383 | 0.71 | FNTA (0.84) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2349999-B1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIV SAARLAND (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-8912186-B2 | Allosteric protein kinase modulators | UNIVERSITAET DES SAARLANDES (DE) | 2014-12-16 | — | — | US | disclosed |
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | UNIVERSITAET DES SAARLANDES (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-2177510-A1 | Allosteric protein kinase modulators | Universität des Saarlandes (DE) | 2010-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046307-A1 | ALLOSTERIC PROTEIN KINASE MODULATORS | AURKC, AURKA, AURKB | ABCB1 2426/4885ABCC1 2842/4885KCNMA1 1122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.