Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.38 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.38 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567483 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL12869368 | 0.76 | — | — | |
| SCHEMBL13827674 | 0.74 | — | — | |
| SCHEMBL26634466 | 0.72 | — | — | |
| SCHEMBL14297362 | 0.72 | — | — | |
| SCHEMBL18321309 | 0.70 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL18711494 | 0.70 | SMN1; SMN2 (0.52) | SMN1; SMN2CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL11710850 | 0.70 | SMN1; SMN2 (0.52) | SMN1; SMN2CHRNB2CHRNA3CHRNA4CHRNB3 | |
| SCHEMBL17793195 | 0.70 | CYP1A2 (0.48) | SMN1; SMN2CYP1A2TDP1KDM4EEPHX2 | |
| SCHEMBL13495511 | 0.70 | CYP1A2 (0.43) | SMN1; SMN2CYP1A2TDP1KDM4EEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265499-B1 | POLYMERIZING MIXTURE | MENICON CO., LTD. (JP) | 2001-07-24 | — | — | US | claimed |
| EP-0921134-B1 | Process for producing a shaped product | MENICON CO LTD (JP) | 2004-04-07 | — | — | EP | disclosed |
| US-6265499-B1 | POLYMERIZING MIXTURE | MENICON CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0921134-A1 | Process for producing a shaped product | Menicon Co., Ltd. (JP) | 1999-06-09 | — | — | EP | disclosed |