SCHEMBL6567774

SCHEMBL6567774

C=C(CC(C)NC(=O)OCc1ccccc1)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.51
CTSS P25774 4/20 0.50
CTSL P07711 3/20 0.50
CTSK P43235 5/20 0.49
ELANE P08246 2/20 0.48
CTRB1 P17538 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
CTSB P07858 2/20 0.46
PSMB1 P20618 1/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
PRTN3 P24158 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4173427 0.86 ATM (0.56) ATMCTSSCTSLCTSKELANE
SCHEMBL6841162 0.86 ATM (0.56) ATMCTSSCTSLCTSKELANE
SCHEMBL5194569 0.83 ATM (0.58) ATMCTSSCTSLCTSKELANE
SCHEMBL4184372 0.83 ATM (0.58) ATMCTSSCTSLCTSKELANE
SCHEMBL265847 0.83 ATM (0.58) ATMCTSSCTSLCTSKELANE
SCHEMBL6841182 0.81 ATM (0.56) ATMCTSSCTSLCTSKELANE
SCHEMBL8972716 0.81 ATM (0.56) ATMCTSSCTSLCTSKELANE
SCHEMBL856096 0.80 ATM (0.58) ATMCTSSCTSLCTSKELANE
SCHEMBL2627372 0.80 ATM (0.58) ATMCTSSCTSLCTSKELANE
SCHEMBL4426192 0.80 ATM (0.58) ATMCTSSCTSLCTSKELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1147076-B1 ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES OKANO TERUO PROF (JP) 2004-03-31 EP disclosed
US-6495645-B1 INCORPORATING MANY SIDE FUNCTIONAL GROUPS WHILE MAINTAINING SENSITIVE TEMPERATURE RESPONSE Okano, Terou (JP) 2002-12-17 US disclosed
EP-1147076-A1 ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES Amersham Pharmacia Biotech K.K. (JP) 2001-10-24 EP disclosed
WO-2000043355-A1 ACRYLAMIDE DERIVATIVES AND POLYMERS CONTAINING SAID DERIVATIVES AMERSHAM PHARMACIA BIOTECH K.K. (JP) 2000-07-27 WO disclosed