Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 7/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 6/20 | 0.53 |
| ▸ | CTSL | P07711 | 5/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.52 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856096 | 1.00 | ATM (0.58) | ATMCTSKCA12CA1CA2 | |
| SCHEMBL2627372 | 1.00 | ATM (0.58) | ATMCTSKCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL3557214 | 0.98 | ATM (0.57) | ATMCTSKCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL3557210 | 0.98 | ATM (0.57) | ATMCTSKCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL3558669 | 0.98 | ATM (0.57) | ATMCTSKCA12CA1CA2 | |
| SCHEMBL18381502 | 0.88 | ATM (0.59) | ATMCTSKCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL5241109 | 0.87 | ATM (0.58) | ATMCTSKCA12CA1CA2 | |
| SCHEMBL13572927 | 0.86 | ATM (0.59) | ATMCTSKCTRB1ELANECTSS | |
| SCHEMBL5268187 | 0.86 | ATM (0.59) | ATMCTSKCA12CA1CA2 | |
| SCHEMBL6407665 | 0.86 | ATM (0.59) | ATMCTSKCTRB1ELANECTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834391-B2 | Pantothenamide analogues | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-12-05 | — | — | US | disclosed |
| US-11834391-B2 | Pantothenamide analogues | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-12-05 | — | — | US | disclosed |
| US-11834391-B2 | Pantothenamide analogues | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-12-05 | — | — | US | disclosed |
| CN-113286778-B | Ubiquitin analogs | MMV疟疾药物投资公司 | 2023-09-22 | — | — | CN | disclosed |
| EP-3906225-B1 | PANTOTHENAMIDE ANALOGUES | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2023-07-05 | — | — | EP | disclosed |
| EP-3906225-B1 | PANTOTHENAMIDE ANALOGUES | MEDICINES FOR MALARIA VENTURE MMV (CH) | 2023-07-05 | — | — | EP | disclosed |
| US-20230159437-A1 | PANTOTHENAMIDE ANALOGUES | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-05-25 | — | — | US | disclosed |
| US-20230159437-A1 | PANTOTHENAMIDE ANALOGUES | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-05-25 | — | — | US | disclosed |
| US-20230159437-A1 | PANTOTHENAMIDE ANALOGUES | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-05-25 | — | — | US | disclosed |
| US-11572336-B2 | Pantothenamide analogues | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2023-02-07 | — | — | US | disclosed |
| WO-2020141155-A1 | PANTOTHENAMIDE ANALOGUES | MMV MEDICINES FOR MALARIA VENTURE (CH) | 2020-07-09 | — | — | WO | disclosed |
| EP-3674288-A1 | PANTOTHENAMIDE ANALOGUES | MMV Medicines for Malaria Venture (CH) | 2020-07-01 | — | — | EP | disclosed |
| EP-3674288-A1 | PANTOTHENAMIDE ANALOGUES | MMV Medicines for Malaria Venture (CH) | 2020-07-01 | — | — | EP | disclosed |
| US-20130012485-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2013-01-10 | — | — | US | disclosed |
| CN-101610761-A | 1-amino methyl-L-phenyl-cyclohexane-derivant as the DDP-IV inhibitor | NOVARTIS AG (CH) | 2009-12-23 | — | — | CN | disclosed |
| EP-2124913-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | Novartis AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077597-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
| US-20050250765-A1 | Diazepinones as antiviral agents | CHO HIDETSURA | 2005-11-10 | — | — | US | disclosed |
| US-20040116410-A1 | Diazepinones as antiviral agents | CHO HIDETSURA (JP) | 2004-06-17 | — | — | US | disclosed |
| WO-2002014324-A2 | DIAZEPINONES AS ANTIVIRAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050250765-A1 | Diazepinones as antiviral agents | ZC3HAV1, ECI1, ZC3HAV1L | ATM 4785/4885CTSK 2200/4885CA12 2276/4885 |
| US-11572336-B2 | Pantothenamide analogues | NAMPT, VKORC1, NME4 | ATM 4720/4885CTSK 2108/4885CA12 4644/4885 |
| US-20130012485-A1 | ORGANIC COMPOUNDS | DPP4, DPP3, DPP7 | ATM 4560/4885CTSK 563/4885CA12 953/4885 |
| US-11834391-B2 | Pantothenamide analogues | NAMPT, VKORC1, NME4 | ATM 4720/4885CTSK 2108/4885CA12 4644/4885 |
| US-20230159437-A1 | PANTOTHENAMIDE ANALOGUES | NAMPT, VKORC1, NME4 | ATM 4720/4885CTSK 2108/4885CA12 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.