SCHEMBL6567848

SCHEMBL6567848

COC(=O)c1ncccc1OSC(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.54
NFE2L2 Q16236 1/20 0.43
TDP1 Q9NUW8 1/20 0.40
PKM P14618 1/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 3/20 0.40
KMT2A Q03164 3/20 0.39
MEN1 O00255 1/20 0.39
MAP2K1 Q02750 1/20 0.38
ALOX15 P16050 1/20 0.38
HTT P42858 1/20 0.38
TLR7 Q9NYK1 1/20 0.38
ACLY P53396 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312146 0.82 L3MBTL1 (0.60) L3MBTL1NFE2L2TDP1PKMALDH1A1
SCHEMBL31471005 0.82 L3MBTL1 (0.53) L3MBTL1NFE2L2KMT2AMAP2K1ALOX15
Hydrochloric Acid SCHEMBL11097642 0.81 L3MBTL1 (0.58) L3MBTL1NFE2L2TDP1PKMALDH1A1
SCHEMBL1173445 0.79 L3MBTL1 (0.50) L3MBTL1NFE2L2ALDH1A1KMT2A
SCHEMBL3653582 0.78 L3MBTL1 (0.58) L3MBTL1TDP1ALDH1A1KDM4EKMT2A
SCHEMBL535696 0.77 L3MBTL1 (0.48) L3MBTL1NFE2L2TDP1PKMALDH1A1
SCHEMBL28269519 0.77 L3MBTL1 (0.54) L3MBTL1TDP1PKMALDH1A1KDM4E
SCHEMBL17028439 0.76 L3MBTL1 (0.53) L3MBTL1TDP1KDM4EKMT2AMAP2K1
SCHEMBL3602782 0.75 L3MBTL1 (0.55) L3MBTL1ALDH1A1KDM4EKMT2AMEN1
SCHEMBL2346222 0.75 L3MBTL1 (0.55) L3MBTL1NFE2L2TDP1ALDH1A1MAP2K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1484381-A1 PHOSPHORS, PROCESS FOR PRODUCTION THEREOF, PHOSPHORESCENT COMPOSITIONS AND ARTICLES MADE BY USING THE SAME JSR Corporation (JP) 2004-12-08 EP disclosed
US-20040106006-A1 Phosphors, process for production thereof, phosphorescent compositions and articles made by using the same JSR CORPORATION (JP) 2004-06-03 US disclosed